Normal hemostasis and coagulation hemostasis 1. Vessel wall (1) vessel spasm: reflex spasm SHT↑s| ow down blood flow (2) subendothelial connective tissue encouraging platelet adhesion, activation aggregation (3)releasing TF, activating FXIl triggering intrinsic and extrinsic pathway (4) pression of haematomaNormal hemostasis and coagulation • hemostasis: 1. Vessel wall： （1）vessel spasm: reflex spasm S-HT↑ slow down blood flow （2）subendothelial connective tissue： encouraging platelet adhesion, activation, aggregation （3）releasing TF, activating FⅫ： triggering intrinsic and extrinsic pathway （4）pression of haematoma