M.C. White, Chem 153 Overview -289- Week of november 11. 2002 Functionalization of terminal alkynes via migratory insertion /reductive elimination sequence? H H t h-H H H LMH R Silylformylation +H--SiR3+ LnM-SiR3 MIL,M SiR3 MI Ln(SiR3)M R LnyF HM.C. White, Chem 153 Overview -289- Week of November 11, 2002 Functionalization of terminal alkynes via migratory insertion /reductive elimination sequence? LnM H R MLn H H H MI R H H + H H Hydrogenation RE R R LnM H R R LnM H MI R H RE + H H H H H Silylformylation H SiR3 C O R + + LnM SiR3 R CO LnM SiR3 CO R SiR3 R O Ln(SiR3)M H MI MI RE SiR3 R O H Hydroacylation H LnM H MI O R' O R' + RE masked R R MLn O R' R H R H R' O