CYP21P RP2 CYP21 RPl C4A C4B TNXA TNXB B Normal 21-Hydroxylase defie 2 3456 89 10 Nonclassic P30L V281L Simple virilizing 1172N →g 1236N R356 Salt wasting V237E M239K GlloA8nt F306+1ntQ318X Figure. The Chromosomal Region of 6p21.3 Containing the 21-Hydroxylase Genes(Panel a), 21-Hydroxylase Genes Undergoing an Unequal Crossover during Meiosis(Panel B), and Mutations in Steroid 21-Hydroxylase Causing Congenital Adrenal Hyperplasia(Panel C)Figure . The Chromosomal Region of 6p21.3 Containing the 21-Hydroxylase Genes (Panel A), 21-Hydroxylase Genes Undergoing an Unequal Crossover during Meiosis (Panel B), and Mutations in Steroid 21-Hydroxylase Causing Congenital Adrenal Hyperplasia (Panel C)