Diffuse hyperplastic goiter 1. Diffuse, symmetric enlargement of the gland; <150g 2. follicle are lined by crowded columnar cells, which may pile up and form projections. There is only little colloid in the folliceDiffuse hyperplastic goiter 1. Diffuse，symmetric enlargement of the gland; <150g 2. follicle are lined by crowded columnar cells, which may pile up and form projections. There is only little colloid in the follice