Colorectal Cancer(CRC) Factors associated with increased risk Age(90% diagnoses in individuals >50 years old) personal or first-degree family history of crc,or adenomas, polyps or inflammatory bowel disease Hereditary conditions Familial adenomatous polyposis ( FAP) ynch syndrome (hereditary nonpolyposis colorectal cancer, HNPCC) -Ulcerative colitis -Obesity, physical inactivity High-fat or low-fiber diet, inadequate intake of fruits and vegetables American Cancer Society Cancer Facts Figures 2005 National Cancer Institute. PDQ Physician Statement.Colorectal Cancer (CRC) • Factors associated with increased risk —Age (>90% diagnoses in individuals >50 years old) —Personal or first-degree family history of CRC, or adenomas, polyps or inflammatory bowel disease —Hereditary conditions • Familial adenomatous polyposis (FAP) • Lynch syndrome (Hereditary nonpolyposis colorectal cancer, HNPCC) —Ulcerative colitis —Obesity, physical inactivity —High-fat or low-fiber diet, inadequate intake of fruits and vegetables American Cancer Society. Cancer Facts & Figures 2005. National Cancer Institute. PDQ® Physician Statement