Chiral pharmaceuticals Dramatic examples of how a change in chirality can affect the biological properties of a molecule are seen in many drugs Fluoxetine,a heavily prescribed medication sold under the trade name Prozac -Racemic fluoxetine is an effective antidepressant but has no activity NHCH3 against migraine -The pure S F30 enantiomer works well in preventing (S)-Fluoxetine migraine偏头痛 (prevents migraine) 2007 Thomson Higher Educalion Chiral pharmaceuticals ™Dramatic examples of how a change in chirality can affect the biological properties of a molecule are seen in many drugs ™Fluoxetine, a heavily prescribed medication sold under the trade name Prozac „Racemic fluoxetine is an effective antidepressant but has no activity against migraine „The pure S enantiomer works well in preventing migraine偏头痛