国生 国生一 Quality control of tablets ·Appearance 圈Appearance ·Crushing strength ·Size ·Disintegration ·Friability .Shape ·Dissolution ·Color ·Weight variation Marking Drug content uniformity 国生一 国话生一 图Crushing strength 加压 ④Disintegration ·Fracture force 画日日：日 Monsanto hardness tester ·Tensile strength抗张强度 弹簧 标尺 T=2F/π·DL 一片剂 Tablet disintegration testing apparatus 国生一 国秋生 圈Friability ©Dissolution ·Roche fibrilator refers to the rate and extent of drug dissolving from solid dosage forms in certain solution. Dissolution methods are developed to evaluate the potential in vivo performance of a solid oral dosage form as quality control tests demonstrating the appropriate performance of drug products. 11 Shanghai Jiao Tong University Quality control of tablets • Appearance • Crushing strength • Disintegration • Friability • Dissolution • Weight variation • Drug content uniformity Shanghai Jiao Tong University Appearance • Size • Shape • Color • Marking Shanghai Jiao Tong University Crushing strength • Fracture force • Monsanto hardness tester • Tensile strength抗张强度 Shanghai Jiao Tong University Tablet disintegration testing apparatus Disintegration Shanghai Jiao Tong University Friability • Roche fibrilator Shanghai Jiao Tong University Dissolution • refers to the rate and extent of drug dissolving from solid dosage forms in certain solution. Dissolution methods are developed • to evaluate the potential in vivo performance of a solid oral dosage form • as quality control tests demonstrating the appropriate performance of drug products