Historical Awareness 1690-Nicotine -water extracted from tobacco leaves sprayed on plants as insecticide > 1700's-Strychnine-extracted from plant used to kill rodents 1800's-Arsenic trioxide-weed killer >1800's-Rotenone-extracted from plants as insecticide > 1800's-Pyrethrum-extracted from chrysanthemum as insecticide >1900's-lead arsenate-orchard insecticide A Small Dose of Toxicology A Small Dose of Pesticide-2/29/04 A Small Dose of Toxicology A Small Dose of Pesticide – 2/29/04 ➢ 1690 – Nicotine - water extracted from tobacco leaves sprayed on plants as insecticide ➢ 1700’s – Strychnine – extracted from plant used to kill rodents ➢ 1800’s – Arsenic trioxide – weed killer ➢ 1800’s – Rotenone – extracted from plants as insecticide ➢ 1800’s – Pyrethrum – extracted from chrysanthemum as insecticide ➢ 1900’s – lead arsenate – orchard insecticide Historical Awareness