BEH.462/3. 962J Molecular Principles of Biomaterials Spring 2003 Vesicular mine H2o Alkylamine vesicles 的mi Synthetic vesicular growth does not yet exhibit the control seen in nature o Lack control over ion introduction into local spaces, ability to manipulate vesicle shape on the scale performed by microtubules and other cytoskeletal elements 31 Disk-shaped diatom Vesicular growth diatom facsimile Microemulsion biomineralization Aqueous solutions of biomineral emulsified by an organic surfactant in an organic phase Mineralization occurs from surface of droplet stabilizer and grows inward into aqueous droplet Lecture 11-Inorganic biomaterials 8of12BEH.462/3.962J Molecular Principles of Biomaterials Spring 2003 Lecture 11 – Inorganic Biomaterials 8 of 12 QuickTime™ and a Graphics decompressor are needed to see this picture. Vesicular mineralization Alkylamine vesicles -NH2 H2O H2O • Synthetic vesicular growth does not yet exhibit the control seen in nature: o Lack control over ion introduction into local spaces, ability to manipulate vesicle shape on the scale performed by microtubules and other cytoskeletal elements Disk-shaped diatom Vesicular growth diatom facsimile 30 µm Microemulsion biomineralization • Aqueous solutions of biomineral emulsified by an organic surfactant in an organic phase • Mineralization occurs from surface of droplet stabilizer and grows inward into aqueous droplet