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Xeroderma Pigmentosum Types Type Gene Locus Absent or minimal Type A, I, XPA XPA 9q22.3 DNA repair activity Type B, Il, XPB XPB 2q21 Few patients Most common, 1/3 Type C,Ⅲ1,XPC XPC 3q25 of all patients XPD Second most Type D,ⅣV,XPD ERCC6 19q13.2-q133,10q11 common Type E, V, XPE DDB2 11p12p11 Type F, VI, XPF ERCC4 16p1331313 RAD2 Type G, Vil, XPG ERCC 13q33 Dominant TypeType Gene Locus Type A, I, XPA XPA 9q22.3 Absent or minimal DNA repair activity Type B, II, XPB XPB 2q21 Few patients Type C, III, XPC XPC 3q25 Most common, 1/3 of all patients Type D, IV, XPD XPD ERCC6 19q13.2-q13.3, 10q11 Second most common Type E, V, XPE DDB2 11p12-p11 Type F, VI, XPF ERCC4 16p13.3-p13.13 Type G, VII, XPG RAD2 ERCC5 13q33 Dominant Type Xeroderma Pigmentosum Types
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