21.5 Steroid receptors have ○ severalindependent domains Figure 21. 5 The first finger of cool a steroid receptor controls DNA binding Dimerization specificity of DNA-binding (positions shown in red); the second finger controls specificity of dimerization (positions shown in blue). The expanded view of the first finger shows that 回 discrimination between GRE ■■■■■ 少 Glucocorticoid Estrogen and ere target sequences rests speciFIcIty specificity on two amino acids at the base O Same sequence in both receptors O Different sequence in each receptor 请莘大Figure 21.5 The first finger of a steroid receptor controls specificity of DNA-binding (positions shown in red); the second finger controls specificity of dimerization (positions shown in blue). The expanded view of the first finger shows that discrimination between GRE and ERE target sequences rests on two amino acids at the base. 21.5 Steroid receptors have several independent domains