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2.1Introduction We can think about mapping genes and genomes at several levels of resolution A genetic (or linkage) map identifies the distance between mutations in terms of recombination frequencies A linkage map can also be constructed by measuring recombination between sites in genomIc NA A restriction map is constructed by cleaving DNA into fragments with restriction enzymes and measuring the distances between the sites of cleavage The ultimate map is to determine the sequence of the DNA From the sequence, we can identity genes and the distances between them 消当2.1 Introduction We can think about mapping genes and genomes at several levels of resolution: A genetic (or linkage) map identifies the distance between mutations in terms of recombination frequencies. A linkage map can also be constructed by measuring recombination between sites in genomic DNA. A restriction map is constructed by cleaving DNA into fragments with restriction enzymes and measuring the distances between the sites of cleavage. The ultimate map is to determine the sequence of the DNA. From the sequence, we can identify genes and the distances between them
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