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Question 4 Polydactyly is a trait where an individual develops more than five fingers per hand or toes er foot. The pattern of inheritance of polydactyly is shown in the following pedigree Assume that all individuals marrying in from outside the family do not carry a disease allele. Assume complete penetrance KEY: D normal male ○ normal female affected male affected female ●●■■ a)What is the mode of inheritance of this trait? Circle all that apply. 4 pts Autosomal minant Mitochondrial cessive Sex-limited X-linked y-linked b)What are the genotypes of the numbered individuals? If more than one genotype is possible, write all. Only show the genotype relating to the disease phenotype. Use the letters D, d, x, x, y, yo, M or M to indicate the genotype corresponding to the polydactyly alleles. 8 pts dd Dd c)What is the probability that the unborn individual marked with(?)will have polydactyly, 4 pt if it were male? 0% if it were female? 0%Question 4 Polydactyly is a trait where an individual develops more than five fingers per hand or toes per foot. The pattern of inheritance of polydactyly is shown in the following pedigree. Assume that all individuals marrying in from outside the family do not carry a disease allele. Assume complete penetrance. KEY: normal male normal female affected male affected female 1* 3* 4* 2* ? a) What is the mode of inheritance of this trait? Circle all that apply. 4 pts Autosomal Dominant Mitochondrial Recessive Sex-limited X-linked Y-linked b) What are the genotypes of the numbered individuals? If more than one genotype is possible, write all. Only show the genotype relating to the disease phenotype. Use the letters D, d, XD, Xd , YD, Yd , MD or Md to indicate the genotype corresponding to the polydactyly alleles. 8 pts 1*______Dd_____ 2*_____dd______ 3*____dd_______ 4*_____Dd_____ c) What is the probability that the unborn individual marked with (?) will have polydactyly, 4 pts if it were male?___0%______ if it were female?______0%___ 8
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