Clinical Manifestations The initial symptom is cramping and twitching of muscles around a wound. The patient usually has no fever but sweats profusely and begins to experience pain especially in the area of the wound and around the neck and jaw muscles(trismus). Portions of the body may become extremely rigid, and opisthotonos角弓反张( a spasm In which the head and heels are bent backward and the body bowed forward) is common Complications include fractures, bowel impaction, intramuscular hematoma, muscle ruptures, and pulmonary renal, and cardiac problemsClinical Manifestations ◼ The initial symptom is cramping and twitching of muscles around a wound. The patient usually has no fever but sweats profusely and begins to experience pain, especially in the area of the wound and around the neck and jaw muscles (trismus). ◼ Portions of the body may become extremely rigid, and opisthotonos角弓反张(a spasm in which the head and heels are bent backward and the body bowed forward) is common. ◼ Complications include fractures, bowel impaction, intramuscular hematoma, muscle ruptures, and pulmonary, renal, and cardiac problems