CH3CH2CH2 Biological Oxidation Br----C--- HH Catalyzed by ADH,alcohol dehydrogenase. Oxidizing agent is NAD+,nicotinamide adenine dinucleotide. Ethanol oxidizes to acetaldehyde,then acetic acid,a normal metabolite. Methanol oxidizes to formaldehyde,then formic acid,more toxic than methanol. Ethylene glycol oxidizes to oxalic acid,toxic. Treatment for poisoning is excess ethanol. => Chapter 11 10CH3CH2CH2 C H H Br O H H Chapter 11 10 Biological Oxidation • Catalyzed by ADH, alcohol dehydrogenase. • Oxidizing agent is NAD+ , nicotinamide adenine dinucleotide. • Ethanol oxidizes to acetaldehyde, then acetic acid, a normal metabolite. • Methanol oxidizes to formaldehyde, then formic acid, more toxic than methanol. • Ethylene glycol oxidizes to oxalic acid, toxic. • Treatment for poisoning is excess ethanol. =>