BEH.462/3. 962J Molecular Principles of Biomaterials Spring 2003 Scheme 1. The Schematic Representation of Aminolysis and Layer-by-Layer Self-Assembly Process with Oppositely Charged Polyelectrolytes on an Aminolyzed PLLA Membrane Surface H (CH-C-O) NH HNNH, NhS IPolyanion NHS 2. Wasl NH白 -CH-C-N-CH2 CH2-NH 2+ HO 3. Polycation NHO 4. Wash sd/ NHP PEM-modified poly lactide Lecture 9-polyelectrolyte hydrogels 8of17BEH.462/3.962J Molecular Principles of Biomaterials Spring 2003 H2N-CH CH3 O -(CH -C-O)n - 2-NH2 CH3 O H -CH -C-N-CH2CH2-NH2 + HO￾PEM-modified polylactide 2CH Lecture 9 – polyelectrolyte hydrogels 8 of 17