Higher methylation states autophosphorylate easier, so slowly CheA adapts to its initial level Phosphorylation high CheA high CheY p tumblin Methylation Ligand Binding 3p 4p T LT 2p LT LT Figure 4 of Spiro, P. A, J.S. Parkinson, and H. G. Othmer A model of excitation and adaptation in bacterial chemotaxis. Proc Natl Acad SciU S A 94, no. 14(Jul 8, 1997): 7263-8 Copyright(1997) National Academy of Sciences, U.S.AHigher methylation states autophosphorylate easier, so slowly CheA p adapts to its initial level high CheA p, high CheY p, tumbling Copyright (1997) National Academy of Sciences, U. S. A. Figure 4 of Spiro, P. A., J. S. Parkinson, and H. G. Othmer. "A model of excitation and adaptation in bacterial chemotaxis." Proc Natl Acad Sci U S A 94, no. 14 (Jul 8, 1997): 7263-8