Single nucleotide polymorphism (SNP) ___SNP is the most common form of genetic variation in the human genome A variation in a single nucleotide that occurs at a specific position in the genome A Key to Human Individuality Base mutation SNP A key to interindividual variations in drug 2 metabolism and response 430C>T(Arg144Cys) ·CAGCTAAC币 CYP2C9*2 A:Adenine T:Thymine G:Guanine No or decreased enzymatic activity C:CytosineSingle nucleotide polymorphism (SNP) A variation in a single nucleotide that occurs at a specific position in the genome A Key to Human Individuality A key to interindividual variations in drug ____SNP is the most common form of genetic variation in the human genome Base mutation metabolism and response A: Adenine T: Thymine G: Guanine C: Cytosine C A G C C C A A C T 5’ 3’ 430C>T (Arg144Cys) Arg144Cys) No or decreased enzymatic activity T CYP2C9*2