NOESY 90 90 90 at,t2 d1 t1 mix →-1，y-1,c0s245-1.c0s24 0Ey-12.c0s244→12，c0s24 Mixing time:~80%of TlNOESY Mixing time: ~80% of T1 2 1 1 ˆ 2 2 1 1 1 1 1 ˆ 2 1 1 1 ˆ 1 ˆ 2 1 cos cos cos cos I t I t I I I t I t y Ix z NOE z Ix y Ix y Ix z ⎯ ⎯→−  ⎯⎯→  ⎯⎯→− ⎯⎯→−  ⎯⎯→−     