The SRY DNA binding(HMG box domain bound to a consensus sequence. The three alpha-helices bind to the minor groove of the DNA double helix and bend and unwind the dna. Alpha-helices are coloured red loop regions are coloured silver; the two strands of the dna double helix are coloured green and blue to emphasise the bend 烤界 angle produced Residues that cause male-to-female sex reversal when mutated are coloured purpleThe SRY DNA binding (HMG￾box) domain bound to a consensus sequence. The three alpha-helices bind to the minor groove of the DNA double helix and bend and unwind the DNA. Alpha-helices are coloured red, loop regions are coloured silver; the two strands of the DNA double helix are coloured green and blue to emphasise the bend angle produced. Residues that cause male-to-female sex reversal when mutated are coloured purple