Fragile X syndrome Children from different ethnic groups have similar characteristics. note the prominent and elongated ears and long faces A caucasian boy with fragile X syndrome An asian boy A hispanic boy with fragile x syndrome with fragile x syndrome The promoter region of the FMR1 gene contains repeats of a specific sequence (cytosine-guanine-guanine or CGG)that, when normal, controls the activity level of the gene in building FMRP. The number of repeated sequences in the promoter region varies from person to person Most people who do not have Fragile X have between six and 40 CGG repeats, with the average being about 30 repeats in the promoter region The larger number of repeats(more than 200) inactivates the gene. The inactivation process is caused by methylation. When the gene is inactivated, the cell may make little or none of the needed FMRPA caucasian boy with fragile X syndrome. An asian boy with fragile X syndrome. A hispanic boy with fragile X syndrome. Fragile X syndrome The promoter region of the FMR1 gene contains repeats of a specific sequence (cytosine-guanine-guanine or CGG) that, when normal, controls the activity level of the gene in building FMRP. The number of repeated sequences in the promoter region varies from person to person. Most people who do not have Fragile X have between six and 40 CGG repeats, with the average being about 30 repeats in the promoter region. The larger number of repeats (more than 200) inactivates the gene. The inactivation process is caused by methylation. When the gene is inactivated, the cell may make little or none of the needed FMRP. Children from different ethnic groups have similar characteristics. Note the prominent and elongated ears and long faces