Solved Problem 1 Suggest the most appropriate method for each of the following laboratory syntheses. (a)cyclopentanol ->cyclopentanone Solution Many reagents are available to oxidize a simple secondary alcohol to a ketone.For a laboratory synthesis,however,dehydrogenation is not practical,and cost is not as large a factor as it would be in industry.Most labs would have chromium trioxide or sodium dichromate available,and the chromic acid oxidation would be simple.PCC and the Swern oxidation would also work,although these reagents are more complicated to prepare and use. OH NazCr207> H2SO4 cyclopentanol (or PCC. cyclopentanone or Swern) Chapter 11 13Chapter 11 13 Suggest the most appropriate method for each of the following laboratory syntheses. (a) cyclopentanol ––––––> cyclopentanone Many reagents are available to oxidize a simple secondary alcohol to a ketone. For a laboratory synthesis, however, dehydrogenation is not practical, and cost is not as large a factor as it would be in industry. Most labs would have chromium trioxide or sodium dichromate available, and the chromic acid oxidation would be simple. PCC and the Swern oxidation would also work, although these reagents are more complicated to prepare and use. Solved Problem 1 Solution