3/13/2016 yersinia enterocolitica yersinia enterocolitica characteristics of infection characteristics of infection Nonspecific self-limiting diarrhea Nonspecific self-limiting diarrhea May lead to a variety of autoimmune May lead to a variety of autoimmune diseases diseases such as arthritis such as arthritis Risk of these diseases is determined by Risk of these diseases is determined by host host factors such as age and immune factors such as age and immune status status Infectious dose is unknown,possible >104 CFU Infectious dose is unknown Enters the intestinal tract via contaminated Enters the intestinal tract via foods and water contaminated foods and water Stomach acid acts as a barrier to infection yersinia enterocolitica Yersinia enterocolitica characteristics of infection characteristics of infection Symptoms similar to acute appendicitis is Most symptomatic infections occur in seen in children older than 5 years and children under age of 5 adolescents causes diarrhea with low fever and pseudoappendicular syndrome abdominal pain occurs with more virulent strains -diarrhea may be watery to mucoid True appendicitis is rarely associated last from a few days to weeks or with y.enterocolitica months 3/13/2016 5 Yersinia enterocolitica characteristics of infection • Nonspecific self-limiting diarrhea • May lead to a variety of autoimmune diseases such as arthritis • Risk of these diseases is determined by host factors such as age and immune status • Infectious dose is unknown • Enters the intestinal tract via contaminated foods and water Yersinia enterocolitica characteristics of infection • Nonspecific self-limiting diarrhea • M l d f d May lead to a variety of autoimmune diseases such as arthritis • Risk of these diseases is determined by host factors such as age and immune status • Infectious dose is unknown, possible Infectious dose is unknown, possible 10 > 4 CFU • Enters the intestinal tract via contaminated foods and water • Stomach acid acts as a barrier to infection Yersinia enterocolitica characteristics of infection • Most symptomatic infections occur in children under age of 5 - causes diarrhea with low fever and abdominal pain - diarrhea may be watery to mucoid - last from a few days to weeks or months Yersinia enterocolitica characteristics of infection • Symptoms similar to acute appendicitis is seen in children older than 5 years and adolescents pseudoappendicular syndrome occurs with more virulent strains • True appendicitis is rarely associated with Y. enterocolitica