Clinical Features of Cushing's syndrome SYMPTOMS (%Patients) SIGNS (%Patients) weight gain 91 97 Menstrual irregularity 8416 Hirsutism 8128 Generalized 5508 Psychiatric dysfunction Plethora 9430 Backache Moon facies Muscle weakness 2980 Hypertension 7444 Fractures Bruising 62103 Loss of scalp hair Red-purple striae 625 Muscle weakness OTHER FINDINGS (%Patients) Ankle edema Hypertension 74 Pigmentation 4 Diabetes 13 Impaired glucose tolerance test 37 osteoporosis Renal calculi 15Clinical Features of Cushing’s Syndrome (%Patients) (%Patients) (%Patients)