My scientific curiosity took a back seat to athletics through junior high and high school. Gymnastics was a good match to my small build and to my solitary nature I was a member of a team but gymnastics is an individual sport You learn a technique, then a move, and then a routine. And then you perfect it through practice, working mostly alone. I had a very good no nonsense teacher, coach Hayes, who really instilled in me the idea of perfection through practice. I was actually not all that bad, particularly at floor exercise and high bar. I even considered pursuing gymnastics in college, but during my final year of high school I began to wonder what I should pursue for a career attended the University of Massachusetts in Boston for one year and then transferred to brandeis University Brandeis was an eye opening experience for me. For the first time in my life I was in a seriously intellectual environment. The classes tended to be small, intense, and stimulating I discovered that I had a passion for science, and that I was very good at it. I chose Biochemistry as a major and a newly arrived assistant professor named Chris Miller for my honors thesis advisor. He had a little laboratory with big windows and lots of light shining in i studied calcium transport and learned about the cell membrane as an electrode i could see that chris Miller was a man having lots of fun in his daily life and it was inspiring to me and the memory of this stayed with me. But the biggest influence Brandeis had on my life happened in Physics class. There I met my future wife Alice Lee, whose sparkling eyes and sharp mind caught my attention Against Chris Millers advice I went to medical school after Brandeis I studied at tufts University School of Medicine and then at Beth Israel Hospital Boston for house officer training in Internal Medicine. I learned a lot but in the end I should have taken Chris' advice to pursue science. Medicine required a lot of memorization and little analytical problem solving To keep a certain part of my brain active I began to study mathematics, and continue this even today, learning new methods and solving problems with the same disciplined approach I had learned in gymnastics. I started back to science near the end of house officer training working with Jim Morgan studying calcium in cardiac muscle contractility, which was very enjoyable and kept me connected to medicine. But I had a yearning to work on a very basic science problem, which meant I would have to break my medical ties. This was a difficult decision because I had invested so many years in medical education; to abandon it was to admit to myself that I had misspent a big piece of my life. And there were practical considerations as well. It was time finally to get a permanent job; after all, my wife Alice had supported me through years of training. Not to mention I was nearly 30 years old with no real basic science training beyond my Brandeis undergraduate education would I even be able to make it as a scientist?My scientific curiosity took a back seat to athletics through junior high and high school. Gymnastics was a good match to my small build and to my solitary nature. I was a member of a team but gymnastics is an individual sport. You learn a technique, then a 'move', and then a 'routine'. And then you perfect it through practice, working mostly alone. I had a very good no nonsense teacher, coach Hayes, who really instilled in me the idea of perfection through practice. I was actually not all that bad, particularly at floor exercise and high bar. I even considered pursuing gymnastics in college, but during my final year of high school I began to wonder what I should pursue for a career. I attended the University of Massachusetts in Boston for one year and then transferred to Brandeis University. Brandeis was an eye opening experience for me. For the first time in my life I was in a seriously intellectual environment. The classes tended to be small, intense, and stimulating. I discovered that I had a passion for science, and that I was very good at it. I chose Biochemistry as a major and a newly arrived assistant professor named Chris Miller for my honors thesis advisor. He had a little laboratory with big windows and lots of light shining in. I studied calcium transport and learned about the cell membrane as an electrode. I could see that Chris Miller was a man having lots of fun in his daily life and it was inspiring to me, and the memory of this stayed with me. But the biggest influence Brandeis had on my life happened in Physics class. There I met my future wife Alice Lee,whose sparkling eyes and sharp mind caught my attention. Against Chris Miller's advice I went to medical school after Brandeis. I studied at Tufts University School of Medicine and then at Beth Israel Hospital Boston for house officer training in Internal Medicine. I learned a lot but in the end I should have taken Chris' advice to pursue science. Medicine required a lot of memorization and little analytical problem solving. To keep a certain part of my brain active I began to study mathematics, and continue this even today, learning new methods and solving problems with the same disciplined approach I had learned in gymnastics. I started back to science near the end of house officer training working with Jim Morgan studying calcium in cardiac muscle contractility, which was very enjoyable and kept me connected to medicine. But I had a yearning to work on a very basic science problem, which meant I would have to break my medical ties. This was a difficult decision because I had invested so many years in medical education; to abandon it was to admit to myself that I had misspent a big piece of my life. And there were practical considerations as well. It was time finally to get a permanent job; after all, my wife Alice had supported me through years of training. Not to mention I was nearly 30 years old with no real basic science training beyond my Brandeis undergraduate education: would I even be able to make it as a scientist?