TABLE 9.1 Some Pharmaceutical Products of Genetic Engineering Product Comments Alpha-interferon Therapy for leukemia,melanoma,and hepatitis;produced by E.coli and Saccharomyces cerevisiae (yeast). Antitrypsin Assists emphysema patients;produced by genetically modified sheep. Beta-interferon Treatment for multiple sclerosis;produced by mammalian cell culture. Bone morphogenic proteins Induces new bone formation;useful in healing fractures and reconstructive surgery; produced by mammalian cell culture. Colony-stimulating factor (CSF) Counteracts effects of chemotherapy:improves resistance to infectious disease such as AlDS;treatment of leukemia;produced by E.coli and S.cerevisiae. Epidermal growth factor (EGF) Heals wounds,burns,ulcers;produced by E.coli. Erythropoietin (EPO) Treatment of anemia;produced by mammalian cell culture. Factor VIlI Treatment of hemophilia;improves clotting:produced by mammalian cell culture. Gamma-interferon Treatment of chronic granulomatous disease;produced by E.coli. Hepatitis B vaccine Produced by S.cerevisiae that carries hepatitis-virus gene on a plasmid. Human growth hormone (hGH) Corrects growth deficiencies in children;produced by E.coli. Human insulin Therapy for diabetes;better tolerated than insulin extracted from animals;produced by Escherichia coli. Table 9.1.1Table 9.1.1