Initiation Promotion Conversion Progression Defects in Terminal Differentiation Defects in Growth Control Resistance to Cytotoxicity Defects in Programmed cell Death RADIATIoNvIRUs 给疗) CELL INITIATE CLINICAL CANCER CANCER METASTASIS Activation of Proto-Oncogenes Inactivation of Tumor Suppressor Genes Inactivation of Antimetastasis Genes Cancer s 多因素多、多步骤 治疗 多因素