Frederick Sanger Linus Pauling Facts(1918-2013) Facts (1901-1994) Frederick Sanver Linus Carl Pauling The Nobel Prize in Chemistry 198 The Nobel Prize in Chemistry 1954 Bor:13 August 1918,Rendcombe,United Kingdom Portland,OR.USA Died:19 November 2013.Cambridge.United Kingdom Died:19 August 1994.Big Sur.CA.USA Affiliation at the time of the award:MRC Laboratory of Affiliation at the time of the award:California Institute of Molecular Biology,Cambridge,United Kingdom Prize motivation:"for his research into the nature of the chemical bond and its application to the elucidation of the Prize share:1/4 structure of complex substances." Also awarded:The Nobel Prize in Chemistry 1958 Prize share:1/1 Also awarded:The Nobel Peace Prize1962 Work 1955胰岛素一级结构的测定 Work 1951蛋白质的二级结构 19Prize:Proteins,which are molecules made up of chains of amino acids,playivtaloe n 1954 Prize:The development of quantum mechanics during the 90s had a great impact not life processes in our cells.One important protein is insulin,a hormone that regulates sugar only on the field of physics,but also o chemistry.During the 1930s Lims Pauling was among content in blood.Beginning in the 1940s,Frederick Sanger studied the coiposition of the insulin molecule.He used acids to break the molecule into smaller parts,which were separated from one another with the help of electrophoresis and chromatography.Further ahalyses determined the hesryepo ant che amino acid sequences in the motecule's two chains.and in 1955 frederick Sanger identined how the chains are linked tog component of many proteins 1978 Sanger测序法 1954诺贝尔化学奖 turning point in Linus 1980 Prize:An organism's g ilding blocks,known 、o6 priheom r nt as nucleotides.which form DNA mol ules An organism's genome can be mapped b and he was a driving force in the Pugwash.It sought to reduce the role of establishing the order of the within the DNA molecue Frederick Sang de0e3ce2e11995.H1959, method based o nbetnsertedimlo DNAcdhain.butatacr cradAfter nder treaty.which entered into focce 63On the same day,the Norwegian Nobel electrophoresis,the nucleotide sequences in a DNA sample can be identifed arded the Prize that had been hek wr扣0a1962 1962年诺贝尔和平奖 1958、1980年诺贝尔化学奖 person 1imedtwo undivided Nobel Prizes In30 1951 蛋白质的二级结构 1958、1980年诺贝尔化学奖 1962年诺贝尔和平奖 1955 胰岛素一级结构的测定 1978 Sanger 测序法 （1918-2013） （1901-1994） 1954诺贝尔化学奖 生物化学与分子生物学教研室