DNA Replication DNA replication is semi-conservative, one strand serves as the template for the second strand Furthermore, dNA replication only occurs at a specific step in the cell cycle The following table describes the cell cycle for a hypothetical cell with a 24 hr cycle Stage Activ ity Duration G1 Growth and increase in cell size 10 hr DNA synthesis 8 hr G2 Post-DNA synthesis 5 hr M Mitosis DNA replication has two requirements that must be met DNA template 2 Free3′- OH groupDNA Replication DNA replication is semi-conservative, one strand serves as the template for the second strand. Furthermore, DNA replication only occurs at a specific step in the cell cycle. The following table describes the cell cycle for a hypothetical cell with a 24 hr cycle. Stage Activity Duration G1 Growth and increase in cell size 10 hr S DNA synthesis 8 hr G2 Post-DNA synthesis 5 hr M Mitosis 1 hr DNA replication has two requirements that must be met: 1. DNA template 2. Free 3' -OH group