Common signs and symptoms Cretinism: a situation induced by a insufficiency of thyroid hormone at birth and during minority, execute growth, twined facial features, increased tongue and mental detainment Adult Fatigue, weakness, weight gain, cold intolerance Coarse, dry hair, dry and rough pale skin, hair loss Muscle cramps and frequent muscle aches Constipation(便秘) Depression Memory loss Abnormal menstrual cycles, decreased libidoCommon signs and symptoms Cretinism: a situation induced by a insufficiency of thyroid hormone at birth and during minority, execute growth, twined facial features, increased tongue and mental detainment Adult: Fatigue, weakness, weight gain, cold intolerance Coarse, dry hair, dry and rough pale skin, hair loss Muscle cramps and frequent muscle aches Constipation(便秘) Depression Memory loss Abnormal menstrual cycles, decreased libido