目 Mechanism of Action曹 General aspects Sphere of influence Some act locally, killing wbc nearby Others help organism to spread in host itssues by degrading connective tissue Still others are disseminated very far from site where synthesized Diphtheria toxin made in throat, but acts on heart and brain BIOL 533 Lecture 9BIOL 533 12 Lecture 9 Mechanism of Action • General aspects – Sphere of influence • Some act locally, killing wbc nearby • Others help organism to spread in host itssues by degrading connective tissue • Still others are disseminated very far from site where synthesized – Diphtheria toxin made in throat, but acts on heart and brain