ADRENAL CORTICOIDS 1563 Existence of adrenal gland discovered by eustachio 1849 Addison attributed"bronzed skin"disease to malfunctioning Adrenal glands 1856 Brown-Sequard removed adrenals of cats and dogs who promptly died proving properly functioning adrenals essential for survival 1894 Adrenal divided into medulla secreting adrenaline and the cortex 1938 Reichstein isolates 29 new substances from adrenal cortex all are steroids 1948 Kendall isolates pure cortisone 1950 Kendall, Reichstein and Hench awarded Nobel prize for medicineADRENAL CORTICOIDS 1563 Existence of adrenal gland discovered by Eustachio 1849 Addison attributed “bronzed skin” disease to malfunctioning Adrenal glands 1856 Brown-Sequard removed adrenals of cats and dogs who promptly died proving properly functioning adrenals essential for survival 1894 Adrenal divided into medulla secreting adrenaline and the cortex. 1938 Reichstein isolates 29 new substances from adrenal cortex all are steroids 1948 Kendall isolates pure cortisone 1950 Kendall, Reichstein and Hench awarded Nobel prize for medicine