N Finney, D. A. Evans The Corey Addendum to the Cyclization Process Chem 206 Squalene Oxide Cyclase -Cornforth Proposal: ACIEE, 1968, 903 Corey-Virgil Revision: JACS 1991, 113, 4025-4026: 8171-8172 Me X-Enz squalene oxide in vivo stereocenter in question lanosterol Me 81 kcal/mol (MM2) anti-migratiol 17 kcal mol anti-migration Sir John Cornforth That outpost of empire Australia, If you are anxious for over-exposure, produces some curious mammalia, to prepublication disclosure, to good food and good drink, the blood-sucking bat, without leisure to think and aurthur birch. inter alia try IUPAC symposia 32A-08-Revised Soc 12/8/00 8: 57 AMMe Me HO Me Me Me Me H Me H Me H Me Me HO Me H Me H Me H H Me Me HO Me H Me Me Me Me Me N. Finney, D. A. Evans The Corey Addendum to the Cyclization Process Chem 206 H squalene oxide Squalene Oxide Cyclase - Cornforth Proposal: ACIEE, 1968, 903. Me Me HO Me H Me H Me H H Me Me Me X-Enz Me Me HO Me H Me H Me H H Me Me Me X-Enz Me Me Me O Me Me Me Me Me H Me Me Me H Me Me HO Me H H Me O Me Me O O Me Me Me Me Me H Me Me Me H Me Me Me Me Me Me HO Me Me Me Me HO Me H Me H Me H Me X H Me Me Corey–Virgil Revision: JACS 1991, 113, 4025-4026; 8171-8172 + lanosterol + lanosterol in vivo Me H H O Me NOT anti-migration anti-migration stereocenter in question 64 kcal/mol 81 kcal/mol (MM2) –17 kcal/mol "That outpost of empire Australia, produces some curious mammalia, the kangaroo rat, the blood-sucking bat, and Aurthur J. Birch, inter alia." If you are anxious for over-exposure, to prepublication disclosure, to good food and good drink, without leisure to think, try IUPAC symposia." Sir John Cornforth: in vivo 32A-08-Revised SqOC 12/8/00 8:57 AM