Introduction Kidney diseases pose a significant global disease burden The most common form, chronic kidney disease(ckd) affects an estimated 10% of adults in many countries and the prevalence IS Increasing Over 250 syndromes and monogenic disorders have been reported to have an increased risk for congenital anomalies of the kidney and urinary tract (caKut)Introduction • Kidney diseases pose a significant global disease burden • The most common form, chronic kidney disease (CKD), affects an estimated 10% of adults in many countries and the prevalence is increasing • Over 250 syndromes and monogenic disorders have been reported to have an increased risk for congenital anomalies of the kidney and urinary tract (CAKUT)