第26卷第5期 李伟雄,等:高性能医用钴基合金强化机理的研究进展 属学报,2015,24(6):1466-1473. TAYLOR K T. An in vitro biomechanical investigation of an WANG Song, LIAO Zhen-hua, LIU Wei-qiang. Research IP35N intramedullary interlocking nail system for repair of progress on thermal oxidation process and wear, corrosion third metacarpal fractures in adult horses]. veterinary Surgery. resistance and bioactivity of biomedical grade titanium alloypj 2002,31(3):211-225 The Chinese Journal of Nonferrous Metals, 2015, 24(6): [13] LESSAR J F, COBIAN K E, MCINTYRE P B, MAYER D W 1466-1473. Medical electrical lead conductor formed from modified MP35N [3]张兴东,刘立斌,王建丽,熊翔.高效组合材料设计方法在 ally:U.s., Patent7138582[P]2006-11-21. 生物钛合金领域的应用[中国有色金属学报,2014,24(11)[14] GARDNER C J, TRISNADI J, KIM T K, BRAMMER K, 2836-2843. REISS L, CHEN L H, JIN S. Controlled metallic nanopillars for ZHANG Xing-dong, LIU Li-bin, WANG Jian-li, XIONG Xiang low impedance biomedical electrode[J]. Acta Biomaterialia, Application of high-efficiency combinatorial approach in 2014,10(5):2296-2303. biomedical titanium alloy u. The Chinese Journal of Nonferrous[l5]梁芳慧.关节置換植入物用材料临床应用现状及发展趋势凹 Metals,2014,24(11):2836-2843 材料科学与工程学报,2009,271):112-117 [4] HU R, ORNBERG A, PAN J. Investigation of influence of small particles in MP35N on the corrosion resistance in synthetic materials used for joint replacement implants[J] Journal of biological environment). Joumal of the Electrochemical Materials Science& Engineering, 2009, 27(1): 112-117. Society,200915610):34l-344 16]郝亮,戴闽,帅浪,程涛,范红先,宗世璋.人工关 [5]史胜风,林军,周炳,王小祥.医用钴基合金的组织结构 节磨损产物金属离子钴、铬对人单核细胞分泌肿瘤坏死因子 及耐腐蚀性能[稀有金属材料与工程,2007,36(1)37-41 的影响[中国组织工程研究与临床康复,2007,111.67-69. SHI Sheng-feng, LiN Jun, ZHOU Bing, WANG Xiao-xiang HAO Liang, DAI Min, SHUAI Lang, CHENG Tao, FAN Microstructure and corrosion resistance of medical cobalt-based Hong-xian,ZONG Shi-zhang. Effect of Co** and Cr"+ alloys. Rare Metal Materials and Engineering, 2007, 36(1)- rtificial joint wear product on tumor necrosis factor secreted 37-41. 6 YOUNKIN C N. Multiphase MP35N alloy for medical Rehabilitative Tissue F implants]. Journal of Biomedical Materials Research, 1974, [17 MARTI A Cobalt-base alloys used in bone surgery]. Injury, 8(3)219-226 2000.31:18-21. [7 SMITH G. Cobalt-nickel base alloys containing chromium and [ 18] SURY P, SEMLITSCH M Corrosion behavior of cast and forged molybdenum: U.S., Patent 3356542[P]. 1967-12-05 cobalt-based alloys for double-alloy joint endoprostheses] 作弹簧的最好材料-MP3N合金门机械工程材 Journal of Biomedical Materials Research, 1978, 12(5) 料,1980,6(1150-57 Ⅻ U Jin-ke. The best material for spring manufacture-MP3N[19黄晶晶,杨柯.镁合金的生物医用硏究门材料导报,2006 alloy]. Materials for Mechanical Engineering, 1980, 6(11) 204):67-69 50-57 HUANG Jing-jing, YANG Ke. Research on magnesium alloys 9]任强,李春福,荣金仿,崔世华,李雅杰.N-Co-CrMo for bio-medical applications[J]. Materials Review, 2006, 20(4) 金MP3N的抗CO2腐蚀性能研究[腐蚀科学与防护技术 67-69 2010,22(5):403-406 [20]袁广银,章晓波,牛佳林,陶海荣,陈道运,何耀华,蒋垚, REN Qiang, LI Chun-fu, RONG Jin-fang, CUI Shi-hua, LI 丁文江.新型可降解生物医用镁合金JDBM的研究进展 Ya-jie. Resistance to COr-induced corrosion of Ni-Co-Cr-Mo 中国有色金属学报,201121(10:2476-2488 alloy MP35NU]. Corrosion Science and Protection Technology YUAN Guang-yin, ZHANG Xiao-bo, NIU Jia-lin, TAO 2010,22(5):403-406. Hai-rong, CHEN Dao-yun, HE Yao-hua, JIANG Yao, DING [10]鲁世强.MP159合金的强化机理和热态变形特性[D]西 Wen-jiang. Research progress of new type of degradable 西北工业大学,1999:1-101 biomedical magnesium alloys JDBMUJ. The Chinese Journal of Nonferrous Metals, 2011, 21(10): 2476-2488 haracteristics of MP159 alloy D]. Xi'an: Northwestern 21] WANG X, KAMENEV K V. Review of modem instrumentation Polytechnical University, 1999: 1-101 for magnetic measurements at high pressure and low [11 ESCALAS F, GALANTE J, ROSTOKER W, PHILIP S MP35N temperature[J]. Low Temperature Physics, 2014, 40(8) A corrosion resistant, high strength alloy for orthopedic surgical 735-746 mpants: Bio-ssay results]. Journal of Biomedical Materials [22 HUANG Y, KONG J F, VENKATRAMAN SS. Biomaterials Research1975,903):303-313 nd design in occlusion devices for cardiac defects: A reviewal [12 GALUPPO L D, STOVER S M, ALDRIDGE A, HEWES C, Acta Biomaterialia, 2014, 10(3): 1088-1101第 26 卷第 5 期 李伟雄，等：高性能医用钴基合金强化机理的研究进展 1051 属学报, 2015, 24(6): 1466−1473. WANG Song, LIAO Zhen-hua, LIU Wei-qiang. Research progress on thermal oxidation process and wear, corrosion resistance and bioactivity of biomedical grade titanium alloy[J]. The Chinese Journal of Nonferrous Metals, 2015, 24(6): 1466−1473. [3] 张兴东, 刘立斌, 王建丽, 熊 翔. 高效组合材料设计方法在 生物钛合金领域的应用[J]. 中国有色金属学报, 2014, 24(11): 2836−2843. ZHANG Xing-dong, LIU Li-bin, WANG Jian-li, XIONG Xiang. Application of high-efficiency combinatorial approach in biomedical titanium alloy[J]. The Chinese Journal of Nonferrous Metals, 2014, 24(11): 2836−2843. [4] HU R, ORNBERG A, PAN J. Investigation of influence of small particles in MP35N on the corrosion resistance in synthetic biological environment[J]. Journal of the Electrochemical Society, 2009, 156(10): 341−344. [5] 史胜凤, 林 军, 周 炳, 王小祥. 医用钴基合金的组织结构 及耐腐蚀性能[J]. 稀有金属材料与工程, 2007, 36(1): 37−41. SHI Sheng-feng, LIN Jun, ZHOU Bing, WANG Xiao-xiang. Microstructure and corrosion resistance of medical cobalt-based alloys[J]. Rare Metal Materials and Engineering, 2007, 36(1): 37−41. [6] YOUNKIN C N. Multiphase MP35N alloy for medical implants[J]. Journal of Biomedical Materials Research, 1974, 8(3): 219−226. [7] SMITH G. Cobalt-nickel base alloys containing chromium and molybdenum: U.S., Patent 3356542[P]. 1967−12−05. [8] 许金科. 制作弹簧的最好材料-MP35N 合金[J]. 机械工程材 料, 1980, 6(11): 50−57. XU Jin-ke. The best material for spring manufacture-MP35N alloy[J]. Materials for Mechanical Engineering, 1980, 6(11): 50−57. [9] 任 强, 李春福, 荣金仿, 崔世华，李雅杰. Ni-Co-Cr-Mo 合 金 MP35N 的抗CO2腐蚀性能研究[J]. 腐蚀科学与防护技术, 2010, 22(5): 403−406. REN Qiang, LI Chun-fu，RONG Jin-fang, CUI Shi-hua, LI Ya-jie. Resistance to CO2-induced corrosion of Ni-Co-Cr-Mo alloy MP35N[J]. Corrosion Science and Protection Technology, 2010, 22(5): 403−406. [10] 鲁世强. MP159 合金的强化机理和热态变形特性[D]. 西安: 西北工业大学, 1999: 1−101. LU Shi-qiang. Strengthening mechanisms and hot deformation characteristics of MP159 alloy[D]. Xi’an: Northwestern Polytechnical University, 1999: 1−101. [11] ESCALAS F, GALANTE J, ROSTOKER W, PHILIP S. MP35N: A corrosion resistant, high strength alloy for orthopedic surgical impants: Bio-ssay results[J]. Journal of Biomedical Materials Research, 1975, 9(3): 303−313. [12] GALUPPO L D, STOVER S M, ALDRIDGE A, HEWES C, TAYLOR K T. An in vitro biomechanical investigation of an MP35N intramedullary interlocking nail system for repair of third metacarpal fractures in adult horses[J]. Veterinary Surgery, 2002, 31(3): 211−225. [13] LESSAR J F, COBIAN K E, MCINTYRE P B, MAYER D W. Medical electrical lead conductor formed from modified MP35N alloy: U.S., Patent 7138582[P]. 2006−11−21. [14] GARDNER C J, TRISNADI J, KIM T K, BRAMMER K, REISS L, CHEN L H, JIN S. Controlled metallic nanopillars for low impedance biomedical electrode[J]. Acta Biomaterialia, 2014, 10(5): 2296−2303. [15] 梁芳慧. 关节置换植入物用材料临床应用现状及发展趋势[J]. 材料科学与工程学报, 2009, 27(1): 112−117. LIANG Fang-hui. Clinical application and development of materials used for joint replacement implants[J]. Journal of Materials Science & Engineering, 2009, 27(1): 112−117. [16] 郝 亮, 戴 闽, 帅 浪, 程 涛, 范红先, 宗世璋. 人工关 节磨损产物金属离子钴、铬对人单核细胞分泌肿瘤坏死因子 的影响[J]. 中国组织工程研究与临床康复, 2007, 11(1): 67−69. HAO Liang, DAI Min, SHUAI Lang, CHENG Tao, FAN Hong-xian, ZONG Shi-zhang. Effect of Co2+ and Cr3+ as artificial joint wear product on tumor necrosis factor secreted from human mononuclear cells[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2007, 11(1): 67−69. [17] MARTI A. Cobalt-base alloys used in bone surgery[J]. Injury, 2000, 31: 18−21. [18] SÜRY P, SEMLITSCH M. Corrosion behavior of cast and forged cobalt-based alloys for double-alloy joint endoprostheses[J]. Journal of Biomedical Materials Research, 1978, 12(5): 723−741. [19] 黄晶晶, 杨 柯. 镁合金的生物医用研究[J]. 材料导报, 2006, 20(4): 67−69. HUANG Jing-jing, YANG Ke. Research on magnesium alloys for bio-medical applications[J]. Materials Review, 2006, 20(4): 67−69. [20] 袁广银, 章晓波, 牛佳林, 陶海荣, 陈道运, 何耀华, 蒋 垚, 丁文江. 新型可降解生物医用镁合金 JDBM 的研究进展[J]. 中国有色金属学报, 2011, 21(10): 2476−2488. YUAN Guang-yin, ZHANG Xiao-bo, NIU Jia-lin, TAO Hai-rong, CHEN Dao-yun, HE Yao-hua, JIANG Yao, DING Wen-jiang. Research progress of new type of degradable biomedical magnesium alloys JDBM[J]. The Chinese Journal of Nonferrous Metals, 2011, 21(10): 2476−2488. [21] WANG X, KAMENEV K V. Review of modern instrumentation for magnetic measurements at high pressure and low temperature[J]. Low Temperature Physics, 2014, 40(8): 735−746. [22] HUANG Y, KONG J F, VENKATRAMAN S S. Biomaterials and design in occlusion devices for cardiac defects: A review[J]. Acta Biomaterialia, 2014, 10(3): 1088−1101