epidemology 160 million patients in the word prevalence: 1%--5%, 1% in china Prevalence in male is similar to that in female The onset is before 12 years of age in the majority Family history could be found in 20% patients Related to allergic rhinitis, eczema and nasal polypepidemiology • 160 million patients in the word • prevalence：1%--5%，1% in china • Prevalence in male is similar to that in female • The onset is before 12 years of age in the majority • Family history could be found in 20% patients • Related to allergic rhinitis, eczema and nasal polyp