Herpes simplex 1 and Herpes simplex 2 Human herpes virus 1 and HHV-2 。 Cold sores or fever blisters (vesicles on lips) Herpes gladiatorum (vesicles on skin) Herpes whitlow(vesicles on fingers) Herpes encephalitis (HHV-2 has up to a 70%fatality rate) HHV-1 can remain latent in trigeminal nerve ganglia HHV-2 can remain latent in sacral nerve ganglia Acyclovir may lessen symptoms• Human herpes virus 1 and HHV-2 • Cold sores or fever blisters (vesicles on lips) • Herpes gladiatorum (vesicles on skin) • Herpes whitlow (vesicles on fingers) • Herpes encephalitis (HHV-2 has up to a 70% fatality rate) • HHV-1 can remain latent in trigeminal nerve ganglia • HHV-2 can remain latent in sacral nerve ganglia • Acyclovir may lessen symptoms Herpes simplex 1 and Herpes simplex 2