Cytokine -mediated effects Cell growth Cell differentiation Cell death Induce non-responsiveness to other cytokines/cells Induce responsiveness to other cytokines/cells Induce secretion of other cytokines Cytokine -mediated effects ◼ Cell growth ◼ Cell differentiation ◼ Cell death ◼ Induce non-responsiveness to other cytokines/cells ◼ Induce responsiveness to other cytokines/cells ◼ Induce secretion of other cytokines