HAART (highly active anti-retroviral therapy) EXamples of approaches: 1. Protease Inhibitor with 1-3 nucleoside reverse transcriptase inhibitor(nrTD) drugs-(Pl +NrTI+ NRTD 2. Double protease Inhibitor combinations with 2 NrTi or a an nrti +nNRTI-(Pl+ PD+ 2NRTI or nNRTI 3. Protease Inhibitor with 2 nrti drugs and a non nucleoside reverse transcriptase inhibitor(nNRTI) PI+ nNRTI +NRTI+ NRTD