4.促进有机化学发展 e NMR/MIS Techniques BTX-E ined BTX-B after 12 years'work,in Brevetoxin BTX-A 于2？年5月日在中国科学上海有机化学研究所法行学术告 1 111 4. 促进有机化学发展 NMR/MS Techniques The architecturally complex molecules provide the driving force for the development of new synthetic strategies/new reactions. Nicolaou Group total synthesized BTX 112 -B after 12 years’ work, in 1995 BTX-B 短裸甲藻毒素 O O O O O O O O O O O H3C O HO CH3 CH3 H3C H3C H3C H3C H H H H H H H H H H H H H H H O H 有机全合成大师-K. C. Nicolaou 113 114 O O O O HO H Me H H H H Me H O O O O Me H H H Me H H H H O O O H H Me OHC Brevetoxin BTX-A 115 •Nicolaou Group total synthesized BTX A after 10 years’ work, in 1998 116 Nicolaou教授于2009年3月26日在中国科学院上海有机化学研究所进行学术报告