Scheme for a 2D MR spectrum Diagonal signals. results from contributions of the magnetization that has not been lo, changed by the mixing sequence A (equal frequency in both dimensions) Cross signals originate from nuclei that exchanged magnetization during the mixing time (frequencies of the first and second nucleus in each dimension B respectively). They indicate an interaction of these two nuclei THMMRScheme for a 2D NMR spectrum THNMR YAN Diagonal signals: results from contributions of the magnetization that has not been changed by the mixing sequence (equal frequency in both dimensions). Cross signals: originate from nuclei that exchanged magnetization during the mixing time (frequencies of the first and second nucleus in each dimension, respectively). They indicate an interaction of these two nuclei