反应机理 1)无催化剂或碱性条件下的加成机理 Addition of a Strong nucleophile to an Aldehyde or Ketone R,δ+8 R C=0=R R O、HMR R C-OH Ni Nua Nu ①D The important aspect of this step is the ability of the carbonyl oxygen atom to accommodate the electron pair of the carbon-oxygen double bondOrganic Chemistry Organic Chemistry Xiamen Xiamen University University 反应机理 1) 无催化剂或碱性条件下的加成机理 C O R' R δ − δ + Nu C O R' R Nu H Nu C OH R' R Nu Addition of a Strong Nucleophile to an Aldehyde or Ketone The important aspect of this step is the ability of the carbonyl oxygen atom to accommodate the electron pair of the carbon-oxygen double bond