PLURIPOTENT HEMATOPOIETIC STEM CELL Self-renewal LYMPHOID MYELOID Endomitotic replication Monocyte Reticulocyte Megakaryocyt Bcell Tcell Platelets Basophil Neutrophil Eosinophil Erythrocyte Macrophage Lymphocytes Granulocytes Strachan T,Read A 2003 Dm72008 • Strachan T, Read A 2003