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11.Which of the following is not limited to the synthesis of primary amines(R-NHor Ar-NH2)(i.e.,which,if any,can be used to make 2 or 3 amines)? Reduction of nitro groups with Fe/HCI Ans:B 12.What product would result from the Hofmann elimination of the following quaternary ammonium hydroxide HC、+ heat CH CHa CH3 CH- Page7Page 7 11. Which of the following is not limited to the synthesis of primary amines (R-NH2 or Ar-NH2) (i.e., which, if any, can be used to make 2° or 3° amines)? A) Gabriel synthesis B) Reduction of amides with LAH C) Hofmann rearrangement D) Reduction of nitriles with LAH E) Reduction of nitro groups with Fe/HCl Ans: B 12. What product would result from the Hofmann elimination of the following quaternary ammonium hydroxide? CH3 N H3C CH3 CH3 + ? - OH heat A) CH3 B) CH3 C) H2N CH3 D) CH2 E) Ans: D
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