Giant acroadenoma side-view MRI (5cm) Macropituitary adenoma:patient 3 Most pituitary adenomas occur spontaneously,not inherited. Cases of familial pituitary tumorsare rare Multiple Endocrine Neoplasia type 1(MEN 1)is a rare condition characterized by simultaneous tumors of the pituitary,pancreas and parathyroid glands.多发性内分泌腺病1型Macropituitary adenoma： nMost pituitary adenomas occur spontaneously, not inherited. nCases of familial pituitary tumorsare rare. nMultiple Endocrine Neoplasia type 1 (MEN 1) is a rare condition characterized by simultaneous tumors of the pituitary, pancreas and parathyroid glands