B Cell Receptor (BCR) ■Pre-BCR Iga(CD79a)and IgB(CD 79b) Associated with Ig molecules on all cells of the B cell lineage Do not bind Ag Signal transduction-transmit signal into cell after binding of Ag to the v regions of Ig H and L chains Surrogate light chains +u chain B-Cell Receptor ,H chain of the BCR may be p,δ，Y,,oreB Cell Receptor (BCR) ◼ Pre –BCR ◼ Iga (CD79a) and Igb (CD 79b) ◼ Associated with Ig molecules on all cells of the B cell lineage ◼ Do not bind Ag ◼ Signal transduction – transmit signal into cell after binding of Ag to the V regions of Ig H and L chains ◼ Surrogate light chains + m chain ◼ B-Cell Receptor ◼ H chain of the BCR may be m, d, g, a, or e