Molecules ? Image removed due to copyright considerations. See Levchenko, A, and P A Iglesias Models of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils Biophys J.82(1Pt1)(Jan2002):50-63 receptor binding→ G-protein activation> activation of p13K (activator)-> activation of pten (inhibitor)-> P3-R*(binding Ph domains)Molecules ?? Image removed due to copyright considerations. See Levchenko, A., and P. A. Iglesias. "Models of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils." Biophys J. 82 (1 Pt 1)(Jan 2002): 50-63. receptor binding → G-protein activation → activation of PI3K (activator) → activation of PTEN (inhibitor) → P3 ~ R* (binding PH domains) 6