3 Mixed Claisen Condensations q- the mixed Claisen condensation of two different esters is similar to the mixed aldol condensation of two different aldehydes or ketones. Mixed claisen condensations are generally successful only when one of the two ester components has no alpha hydrogens and thus cant form an enolate ionOrganic Chemistry Organic Chemistry Xiamen Xiamen University University Mixed Claisen Condensations „ The mixed Claisen condensation of two different esters is similar to the mixed aldol condensation of two different aldehydes or ketones.Mixed Claisen condensations are generally successful only when one of the two ester components has no alpha hydrogens and thus can’t form an enolate ion