Dentin caries o Develops from enamel caries and cementum caries o Pathological progress differs from enamel caries: o Relatively high organic contents-proteolytic break down of the collagenous matrix 2 Contain dentinal tubules--Carious process extend along dentinal tubules, progress rapidly o Pulpodentinal complex--Defence reaction e Cone-shaped lesion, the base at the edj, the apex of the cone towards the pulp cavity Department of Oral Pathology, Shandong University http://1.51.214.13Department of Oral Pathology, Shandong University 2 http://1.51.214.13  Develops from enamel caries and cementum caries.  Pathological progress differs from enamel caries: ①Relatively high organic contents——proteolytic break down of the collagenous matrix ②Contain dentinal tubules——Carious process extend along dentinal tubules, progress rapidly ①Pulpodentinal complex——Defence reaction  Cone-shaped lesion, the base at the EDJ, the apex of the cone towards the pulp cavity