Differential diagnosis Nutritional origin Prolonged diet protein deficient hypoproteinemia Intensified by the beriberi(脚气病) heart disease Reduced effective systemic perfusion /arterial blood volume Edema becomes intensified An adequate diet is provided More food more salt ingested Refeeding edema Increased release of insulin Hypokalemia and caloric deficits may also be involvedDifferential diagnosis Nutritional origin • Prolonged diet protein deficient hypoproteinemia • Intensified by the berbiberi (脚气病）heart disease • Reduced effective systemic perfusion / arterial blood volume • Edema becomes intensified: An adequate diet is provided More food more salt ingested Increased release of insulin • Hypokalemia and caloric deficits may also be involved Refeeding edema